一、个人简介

郝志强，男，博士，248cc永利集团讲师。主要研究方向为生物信息学和功能基因组学，参与发表多篇SCI研究论文，参与国家自然科学基金项目一项。在教学方面主要从事本科生《酶工程》《基因工程实验》、《酶工程实验》等课程的教学工作。

二、研究领域

1. lncRNA等非编码RNA的识别及功能研究。主要在动植中利用生物信息学手段进行lncRNAs识别工具开发，利用生物网络 等多种方法分析非编码RNA潜在功能。

2. 地下鼠对地下低氧环境适应的研究。利用高通量组学数据挖掘地下鼠低氧适应关键基因、生物过程、通路等。

三、参与发表的科研论文

[1] Hao Z, Xu L, Zhao L, He J, Li G, Li J. (2021). Transcriptome analysis of the liver ofEospalax fontanierii under hypoxia. PeerJ 9:e11166.

[2] Hao Z, Ming F, Guo J, Li G, He J, Jin G. (2021).Identification and functional analysis of lncRNAs responsive to hypoxia inEospalax fontanierii. Curr. Issues Mol. BIol.

[3] Hao Z, Fan C, Cheng T, Su Y, Wei Q, Li G,et al. (2015). Genome-wide identification, characterization and evolutionary analysis of long intergenic noncoding rnas in cucumber. Plos One, 10(3), e0121800.

[4] Tang B^#,Hao Z^#, Zhu Y, Zhang H, Li G. (2018). Genome-wide identification and functional analysis of circrnas inzea mays. PLoS ONE, 13(12).

[5] Xu L^#,Hao Z^#, Lin J, Zhao Q, Li J. (2019). Transcriptome sequencing ofEpospalax fontanierii to determine hypoxia regulation of cardiac fibrinogen. Molecular Biology Reports, 46(27).

[6] Zhang J^#,Hao Z^#, Yin S, Li G. (2020). Greencircrna: a database for plant CircRNAs that act as miRNA decoys. Database.

[7] Fan C,Hao Z, Yan J, Li G. (2015). Genome-wide identification and functional analysis of lincRNAs acting as miRNA targets or decoys inmaize. BMC Genomics, 16(1), 793.

[8] Lin J, Fan L, Y Han, Guo J,Hao Z, Li J. (2021). The mtorc1/eif4e/hif-1α pathway mediates glycolysis to support brain hypoxia resistance in theGansu Zokor, Eospalax cansus. Frontiers in Physiology, 12, 626240.

[9] Lin J, Yang Q, Guo J, Li M,Hao Z, He J and Li J. (2022) Gut Microbiome Alterations and Hepatic Metabolic Flexibility in theGansu Zokor,Eospalax cansus: Adaptation to Hypoxic Niches. Front. Cardiovasc. Med. 9:814076.

[10] 樊春燕,魏强,郝志强, 李广林. (2014). miRNAs调控lincRNAs的生物信息学预测与功能分析.遗传, 36(12), 1226-1226.

[11] Zhao Y, Hu T, Liu R,Hao Z, Li G. (2021). Biochemical characterization and function of eight microbial type terpene synthases fromlycophyteSelaginella moellendorffii. International Journal of Molecular Sciences, 22(2), 605.

[12] Li G,Hao Z, Fan C, Wu X. (2017). Genome-Wide Function Analysis of lincRNAs as miRNA Targets or Decoys in Plant. Plant Epigenetics. Springer, Cham, Pages 149-162. https://doi.org/10.1007/978-3-319-55520-1_8

[13] Hao Z,Li, G. (2021). Chapter 12 - Genome-wide identification and functional analysis of lincRNAs in cucumber. Long Noncoding RNAs in Plants,Academic Press, Pages 189-196. https://doi.org/10.1016 /B978-0-12-821452-7.00012-X

四、联系方式

通讯地址：陕西省商州区北新街10号248cc永利集团，726000

邮箱：haozhiqiang@snnu.edu.cn